PARICHY LAB

Post-doctoral positions available to study hormonal control over post-embryonic neural crest stem cells, plasticity in cell state, evolution of novel cell types, and mechanisms of pattern formation and cell–cell communication within zebrafish and across Danio species. Positions are funded but prior postdocs also have been successful in securing independent support including NIH NRSA Ruth Kirchstein Individual Fellowships and NIH K99/R00 Awards. Postdocs are expected to develop independent research programs that will follow them to independent positions once their training has completed. Methods used in the lab include super-resolution time-lapse imaging on lab-dedicated microscopes, single cell RNA-sequencing, forward and reverse genetics, conditional manipulation of gene activity and others. A Ph.D. in Biology, Molecular Cell Biology or related field is required by the start date of the appointment. Candidates must have experience with one or more methods routinely used in the laboratory, such as; high resolution imaging (Fluorescence, brightfield), molecular cloning and PCR, next generation library construction, RNA-sequencing and bioinformatics, quantitative RT-PCR, genetic or transgenic analysis, histology, in situ hybridization, microinjection and micro-manipulation, or care and routine developmental genetic methods using model organisms. To apply, visit http://jobs.virginia.edu and search on Posting Number 0623557. Complete a Candidate Profile, attach contact information for 3 references, a cover letter, a CV/Resume, and a Statement of Research Interest. For more information contact David Parichy (dparichy@virginia.edu).

Graduate students. We welcome applications from prospective graduate students interested in the developmental genetics of adult form, stem cells,  cellular interactions, the evolution of developmental mechanisms and other topics using Danio pigmentation, as well as other systems and other vertebrates. The lab is affiliated with three different graduate programs (Biology, Biomedical Sciences, Neurosciences) each having different features. UVA has outstanding current and historical strengths in developmental biology, especially related to mechanisms of morphogenesis and the training environment is excellent. Prospective applicants are encouraged to contact David Parichy (dparichy@virginia.edu) well in advance of submitting program applications.

Senior staff positions for Imaging Specialist, Molecular Biologist, and Genomic/Bioinformatic Scientists. We are seeking Laboratory Specialists as well as Laboratory Specialists Intermediates determined on amount of experience to participate in several projects related to overall goals of the laboratory, including on-going studies of stem cells and pattern formation, while also contributing effort to developing new tools and resources for future projects. Techniques include state of the art genetic screening, CRISPR/Cas9 mutagenesis and transgenic line production, as well as cell transplantation, histological gene expression analysis, super resolution time-lapse imaging, and next generation sequencing including single cell RNA-seq. For Laboratory Specialists a Bachelor's Degree is required as are three years of prior research experience. For Laboratory Specialists

UVA Developmental Biology

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Adler

Grainger

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Keller

Dwyer

Halme

Parichy

Kucenas

DeSimone

Siegrist

Liu

Sutherland

Intermediate a Bachelor's Degree with 6 years of experience is required. Research experience acquired in pursuit of M.A. or Ph.D. may be considered in lieu of non-academic post-baccalaureate experience. Knowledge of one or more methods routinely used in the laboratory, such as: high resolution imaging (fluorescence, brightfield), molecular cloning and PCR, next generation library construction, RNA-sequencing and bioinformatics, quantitative RT-PCR, genetic or transgenic analysis, histology, in situ hybridization, microinjection and micro-manipulation, or care and routine developmental genetic methods using model organisms is required. Applicants must exhibit a strong aptitude for multitasking, planning and time management. Dexterity for precise handling of small objects and small volumes is required. The ability to collect and organize data is essential, as is proficiency in Microsoft Office Suite. Preference will be given to applicants with experience in multiple areas of research or who have specific experience with zebrafish. Applicants with publications from prior research positions or degree programs are highly preferred. Knowledge of Adobe Creative Suite, R, Matlab, Monocle, SAS, JMP, SPSS, FileMaker, CLC Main Workbench, ZEN, Imaris, or ImageJ is preferred. To apply, visit http://jobs.virginia.edu and search Posting Number #0623491, complete the staff application, attach a cover letter, a resume, and contact information for 3 references. For more information contact David Parichy (dparichy@virginia.edu).

Junior staff position for Lab Animal Technician. To assist with daily operations in the fish facility, which maintains over 150 genetic stocks of zebrafish and related species in state of the art aquatic housing comprising more than 1800 tanks. The position requires daily checks of fish health and mechanical systems; routine animal husbandry including feedings; routine maintenance and upkeep of fish-related infrastructure; continuous culturing of live food (rotifers); routine maintenance of genetic stocks; cryopreservation of sperm; screening of stocks for induced mutations and transgenes; selecting progeny for specific traits; adherence to federal, state and laboratory specific animal care and use guidelines. A High School Diploma or equivalent is required, a Bachelor's degree in Biology or related field is preferred. Experience with and knowledge of care of tropical fish or other vertebrates is essential. The ability to learn and perform routine maintenance on large, multi-tank, self-contained aquatic habitats, as well as learn how to perform a basic mechanical inspection of the aquatic system is required. The incumbent must be an observant individual so that possible problems with the habitat systems, or any signs of poor health in the animals can be addressed. The ability to follow set lab policies and procedures and adhere to regulatory guidelines in daily work is essential. The ability to work independently, part of a team, and provide direct support to leaders as needed is required. Dexterity for precise handling of small objects and small volumes is essential. Preference will be given to candidates with at least one year of prior work experience in animal care or veterinary settings, but candidates with knowledge of fish and job experience in service, retail or other areas are encouraged to apply. Knowledge of zebrafish or other tropical fish is strongly desirable. Familiarity with FileMaker is preferred. To apply, visit http://jobs.virginia.edu and search Posting Number #0623447, complete the staff application, attach a cover letter, a resume, and contact information for 3 references. For more information contact David Parichy (dparichy@virginia.edu).

 

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University of Virginia

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Charlottesville VA 22904

 

 

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